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Inside the literature, we identified which the antimicrobial activity of benzofuran derivatives appears to be additional dependent on substitution within the heterocyclic furan ring than on substitution for the aromatic moiety.60 Telvekar and co-personnel investigated a series of benzofuran-3-carbohydrazide derivatives and screened for his or her l

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To acquire analogs of compound X, the starting up acid 2 was reacted using an extra of dimethyl sulphate plus the acquired derivative 3 was subjected into a multidirectional synthesis (Scheme three). In the very first scenario, bromine was introduced into the methyl group to provide a compound 3d, by response with NBS in CCl4. During the response o

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